binding affinity

binding affinity
Фармакология: связывающая способность

Универсальный англо-русский словарь. . 2011.

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  • Affinity — Affinity, in etymology affinity is the opposite of infinity . These two words have the same root coming from the Latin: finis = end . “Affinity” meaning is near to the “finis” e.g. close to the “zero point” in a before assumed space. On the other …   Wikipedia

  • Affinity chromatography — is a method of separating biochemical mixtures and based on a highly specific interaction such as that between antigen and antibody, enzyme and substrate, or receptor and ligand. Contents 1 Uses 2 Principle 3 Batch and column setup …   Wikipedia

  • Affinity maturation — In immunology, affinity maturation is the process by which B cells produce antibodies with increased affinity for antigen during the course of an immune response. With repeated exposures to the same antigen, a host will produce antibodies of… …   Wikipedia

  • Binding potential — In pharmacokinetics and receptor ligand kinetics the binding potential (BP) is a combined measure of the density of available neuroreceptors and the affinity of a drug to that neuroreceptor. Description Consider a ligand receptor binding system.… …   Wikipedia

  • affinity chromatography — A method for purifying specific components in a solution by exploiting their specific binding to known molecule(s). The mixed solution is passed through a column containing a solid medium to which the binding molecule is covalently attached. See …   Glossary of Biotechnology

  • Binding site — In biochemistry, a binding site is a region on a protein, DNA, or RNA to which specific other molecules and ions mdash; in this context collectively called ligands, or more specifically, protein ligands mdash; form a chemical bond.The term… …   Wikipedia

  • Binding constant — The binding constant is a special case of the equilibrium constant K. The equilibrium state of molecular binding, i.e. the balance between the binding and dissociation processes after infinite reaction time, may be formalized as the unbound… …   Wikipedia

  • affinity — An expression of the strength of interaction between two entities, eg. between receptor and ligand or between enzyme and substrate. The affinity is usually characterized by the equilibrium constant association constant or dissociation constant… …   Dictionary of molecular biology

  • affinity labelling — Labelling of the active site of an enzyme or the binding site of a receptor by means of a reactive substance that forms a covalent linkage once having bound. Linkage is often triggered by a change in conditions, for example in photoaffinity… …   Dictionary of molecular biology

  • affinity — 1. In chemistry, the force that impels certain atoms to bind to or unite with certain others to form complexes or compounds; chemical attraction. 2. Selective staining of a tissue by a dye or the selective uptake of a dye, chemical, or other s …   Medical dictionary

  • binding site — in an enzyme or other protein, the three dimensional configuration of specific groups on specific amino acids that binds particular compounds such as substrates or effectors, with high affinity and specificity. Cf. catalytic s …   Medical dictionary


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